Changes in brain function and morphology in patients with recurring herpes simplex virus infections and chronic pain
N Vartiainen, K Kallio-Laine, Y Hlushchuk, E Kirveskari… - PAIN®, 2009 - Elsevier
A recent study described for the first time a patient group that suffered from spontaneous
chronic pain and from recurrent herpes simplex virus (HSV) infections. The patients had pain
in widespread areas on one side of the body and were—due to subtle immunological
abnormalities—susceptible to HSV infections. Although the clinical features of the pain
suggested involvement of the central nervous system, supporting evidence for this was
lacking. The objective of this study was to search for changes in the central nervous system …
chronic pain and from recurrent herpes simplex virus (HSV) infections. The patients had pain
in widespread areas on one side of the body and were—due to subtle immunological
abnormalities—susceptible to HSV infections. Although the clinical features of the pain
suggested involvement of the central nervous system, supporting evidence for this was
lacking. The objective of this study was to search for changes in the central nervous system …