[HTML][HTML] CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation

KA Kovács, M Steinmann, PJ Magistretti… - Journal of Biological …, 2003 - ASBMB
CCAAT/enhancer-binding protein (C/EBP) family members are transcription factors involved
in important physiological processes, such as cellular proliferation and differentiation,
regulation of energy homeostasis, inflammation, and hematopoiesis. Transcriptional
activation by C/EBPα and C/EBPβ involves the coactivators CREB-binding protein (CBP)
and p300, which promote transcription by acetylating histones and recruiting basal
transcription factors. In this study, we show that C/EBPδ is also using CBP as a coactivator …