Diastolic dysfunction and its histopathological correlation in obstructive hypertrophic cardiomyopathy in children and adolescents
SC Menon, BW Eidem, JA Dearani, SR Ommen… - Journal of the American …, 2009 - Elsevier
BACKGROUND: Histopathologic hallmarks of hypertrophic cardiomyopathy (HCM) include
myocyte hypertrophy and disarray as well as interstitial and endocardial fibrosis. Published
correlations between echocardiographic parameters and histopathologic findings are
scarce. METHODS: All patients aged< 20 years (n= 45; 15 female patients; median age, 14
years) with obstructive HCM undergoing septal myectomy at the Mayo Clinic from 2003 to
2007 were identified. A retrospective review of echocardiographic data was performed, and …
myocyte hypertrophy and disarray as well as interstitial and endocardial fibrosis. Published
correlations between echocardiographic parameters and histopathologic findings are
scarce. METHODS: All patients aged< 20 years (n= 45; 15 female patients; median age, 14
years) with obstructive HCM undergoing septal myectomy at the Mayo Clinic from 2003 to
2007 were identified. A retrospective review of echocardiographic data was performed, and …