Diabetic cardiomyopathy revisited

S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc
S Boudina, ED Abel
Circulation, 2007Am Heart Assoc
Diabetes mellitus increases the risk of heart failure independently of underlying coronary
artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying
pathogenesis is partially understood. Several factors may contribute to the development of
cardiac dysfunction in the absence of coronary artery disease in diabetes mellitus. This
review discusses the latest findings in diabetic humans and in animal models and reviews
emerging new mechanisms that may be involved in the development and progression of …
Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac dysfunction in the absence of coronary artery disease in diabetes mellitus. This review discusses the latest findings in diabetic humans and in animal models and reviews emerging new mechanisms that may be involved in the development and progression of cardiac dysfunction in diabetes.
Am Heart Assoc