New insights into the biology of neural stem cells (NSCs) have raised expectations for their
use in the treatment of neurologic diseases. Originally, NSC transplantation was proposed
as a means of replacing cells in central nervous system diseases that result in cell loss.
However, recent data regarding their beneficial effects in various animal models of
neurologic diseases indicate that transplanted NSCs may also attenuate deleterious
inflammation, protect the central nervous system from degeneration, and enhance …