Molecular biology of inflammation and sepsis: a primer

I Cinel, SM Opal - Critical care medicine, 2009 - journals.lww.com
Background: Remarkable progress has been made during the last decade in defining the
molecular mechanisms that underlie septic shock. This rapidly expanding field is leading to
new therapeutic opportunities in the management of severe sepsis. Aim: To provide the
clinician with a timely summary of the molecular biology of sepsis and to better understand
recent advances in sepsis research. Data Selection: Medline search of relevant publications
in basic mechanisms of sepsis/severe sepsis/septic shock, and selected literature review of …