Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane

FG Holz, G Sheraidah, D Pauleikhoff… - Archives of …, 1994 - jamanetwork.com
Objective: Lipids in Bruch's membrane may affect the evolution of age-related macular
disease. To determine whether these show differences in regional distribution, we analyzed
lipid deposits in Bruch's membrane at macular and peripheral sites. Methods: Thin-layer
chromatography was used to measure different lipid classes extracted from macular and
peripheral Bruch's membrane of 32 eye bank eyes. Results: The quantity of lipid extracted
was consistently higher in the macula than in the periphery of human eyes. The total from …