[HTML][HTML] Acute physical stress elevates mouse period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element

T Yamamoto, Y Nakahata, M Tanaka, M Yoshida… - Journal of Biological …, 2005 - ASBMB
In mammals, the circadian and stress systems (both centers of which are located in the
hypothalamus) are involved in adaptation to predictable and unpredictable environmental
stimuli, respectively. Although the interaction and relationship between these two systems
are intriguing and have been studied in different ways since the" pre-clock gene" era, the
molecular interaction between them remains largely unknown. Here, we show by systematic
molecular biological analysis that acute physical stress elevated only Period1 (Per1) mRNA …