The role of NKT cells in tumor immunity

M Terabe, JA Berzofsky - Advances in cancer research, 2008 - Elsevier
NKT cells are a relatively newly recognized member of the immune community, with
profound effects on the rest of the immune system despite their small numbers. They are true
T cells with a T cell receptor (TCR), but unlike conventional T cells that detect peptide
antigens presented by conventional major histocompatibility (MHC) molecules, NKT cells
recognize lipid antigens presented by CD1d, a nonclassical MHC molecule. As members of
both the innate and adaptive immune systems, they bridge the gap between these, and …