Clock gene expressions in the suprachiasmatic nucleus and other areas of the brain during rhythm splitting in CS mice

H Abe, S Honma, M Namihira, S Masubuchi… - Molecular brain …, 2001 - Elsevier
The CS mouse is a mutant strain which displays spontaneous splitting in the circadian
locomotor rhythm under continuous darkness. To clarify whether the rhythm splitting occurs
in the suprachiasmatic nucleus (SCN) where the mammalian circadian clock is located, the
circadian rhythmicities of mammalian clock genes, mPer1, mBMAL1 and mClock, were
examined in the SCN and cerebral cortex during rhythm splitting. The circadian profiles of
the clock genes during rhythm splitting were essentially the same as those observed under …