[CITATION][C] Sites of metformin-stimulated glucose metabolism

C Wilcock, CJ Bailey - Biochemical pharmacology, 1990 - Elsevier
C Wilcock, CJ Bailey
Biochemical pharmacology, 1990Elsevier
Sites of metformin-stimulated glucose metabolism Page 1 Short communications Biochemical
Phormmdogy, Vol. 39. No. 11, pp. 1831-1834, 1990. Printed in Great Britain. Sites of
metformin-stimulated glucose metabolism (Received 4 December 1989; accepted 6 February
1990) 1831 000&2952/W $3.00 + 0.00 0 1990. Pergamon Press plc The antihyperglycaemic
agent metformin (dimethylbiguanide) is now widely used in the treatment of noninsulin-dependent
diabetes mellitus (NIDDM) [ 11. There is evidence that the drug lowers glucose concentrations …
Materials and Methods
Adult male albino MFl mice from a colony maintained at Aston University were used. The mice were housed in an air-conditioned iroom at 22+ 2” with a regular lighting schedule of 12 hr lieht~ 0800-2000 hr1 and 12 hr dark. A
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