The role of c-myc in cell growth
GI Evan, TD Littlewood - Current opinion in genetics & development, 1993 - Elsevier
GI Evan, TD Littlewood
Current opinion in genetics & development, 1993•ElsevierRecent experiments have established that the c-myc oncogene encodes a sequence-
specific DNA-binding protein that interacts with a specific intracellular partner, Max, and
probably manifests its effects through transcriptional modulation. In addition, the range of
biological functions attributed to expression of c-myc has grown to include not only
transformation and mitogenesis but also cell death.
specific DNA-binding protein that interacts with a specific intracellular partner, Max, and
probably manifests its effects through transcriptional modulation. In addition, the range of
biological functions attributed to expression of c-myc has grown to include not only
transformation and mitogenesis but also cell death.
Recent experiments have established that the c-myc oncogene encodes a sequence-specific DNA-binding protein that interacts with a specific intracellular partner, Max, and probably manifests its effects through transcriptional modulation. In addition, the range of biological functions attributed to expression of c-myc has grown to include not only transformation and mitogenesis but also cell death.
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