Lymphocyte subpopulations in the caecum mucosa of rats after infections with Eimeria separata: early responses in naive and immune animals to primary and …

M Shi, S Huther, E Burkhardt, H Zahner - International journal for …, 2001 - Elsevier
This study aimed to characterise the local (intestinal) immune response of rats after primary
and challenge infections with Eimeria separata. Naive rats and rats which had been
immunised by two moderate infections were exposed to a heavy infection with 100 000
oocysts per animal. Necropsies were performed 0, 24 and 48 h after infection and
lymphocyte subpopulations were microscopically quantified in the caecum mucosa after
marking by immunohistological techniques. There was no difference between naive and …