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URL: http://scholar.google.com/scholar_lookup?title=Missense+mutations+that+cause+Van+der+Woude+syndrome+and+popliteal+terygium+syndrome+affect+the+DNA-binding+and+transcriptional+activation+functions+of+IRF6.&year=2009&author=Little&journal=Hum+Mol+Genet.&volume=18&issue=3&pages=535-545&pmid=19036739