Glycerol 3-phosphate acylation in microsomes of type II cells isolated from adult rat lung

JJ Batenburg, JN Den Breejen, RW Yost… - … et Biophysica Acta (BBA …, 1986 - Elsevier
Glycerol 3-phosphate acylation was studied in type II cells isolated from adult rat lung. The
process was found to be largely microsomal. In the microsomes phosphatidic acid is the
main product of glycerol 3-phosphate acylation. Glycerol-3-phosphate acyltransferase is rate
limiting in the phosphatidic acid formation by the microsomes. Type II cell microsomes
incorporate palmitoyl and oleoyl residues into phosphatidic acid at an equal rate if palmitoyl-
CoA and oleoyl-CoA are added separately. However, if palmitoyl-CoA and oleoyl-CoA are …