Synthesis of saturated phosphatidylcholine and phosphatidylglycerol by freshly isolated rat alveolar type II cells
RJ Mason, J Nellenbogen - Biochimica et Biophysica Acta (BBA)-Lipids and …, 1984 - Elsevier
Saturated phosphatidylcholine and phosphatidylglycerol are important components of
pulmonary surface active material, but the relative contributions of different pathways for the
synthesis of these two classes of phospholipids by alveolar type II cells are not established.
We purified freshly isolated rat type II cells by centrifugal elutriation and incubated them with
[1-14 C] palmitate as the sole exogenous fatty acid in one series of experiments or with [9,
10-3 H] palmitate, mixed fatty acids (16: 0, 18: 1 and 18: 2), and [U-14 C] glucose in another …
pulmonary surface active material, but the relative contributions of different pathways for the
synthesis of these two classes of phospholipids by alveolar type II cells are not established.
We purified freshly isolated rat type II cells by centrifugal elutriation and incubated them with
[1-14 C] palmitate as the sole exogenous fatty acid in one series of experiments or with [9,
10-3 H] palmitate, mixed fatty acids (16: 0, 18: 1 and 18: 2), and [U-14 C] glucose in another …