According to the humoral theory of transplantation, antibodies cause allograft rejection.
Publications are cited showing that antibodies:(1) cause hyperacute kidney rejection,(2)
lead to C4d deposits associated with early kidney graft failures,(3) are a good indicator of
presensitization leading to early acute rejections,(4) were present in 96% of 826 patients
who rejected a kidney graft,(5) are associated with chronic rejection in 33 studies of kidney,
heart, lung and liver grafts, and (6) in three studies, appeared in the circulation BEFORE …