[PDF][PDF] Atlasin GTPases shape up ER networks
C Barlowe - Developmental cell, 2009 - cell.com
C Barlowe
Developmental cell, 2009•cell.comThe endoplasmic reticulum (ER) adopts a remarkable array of flattened membrane
structures and branched tubular networks to support cellular function. Recent studies reveal
that the integral membrane atlastin GTPases, which are linked to neurodegenerative
diseases, catalyze membrane fusion and are required for the formation of branched
membrane networks characteristic of the ER.
structures and branched tubular networks to support cellular function. Recent studies reveal
that the integral membrane atlastin GTPases, which are linked to neurodegenerative
diseases, catalyze membrane fusion and are required for the formation of branched
membrane networks characteristic of the ER.
The endoplasmic reticulum (ER) adopts a remarkable array of flattened membrane structures and branched tubular networks to support cellular function. Recent studies reveal that the integral membrane atlastin GTPases, which are linked to neurodegenerative diseases, catalyze membrane fusion and are required for the formation of branched membrane networks characteristic of the ER.
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