Measurement of kidney function

LA Stevens, AS Levey - Medical Clinics, 2005 - medical.theclinics.com
Accurate estimation of kidney function is central to the detection, evaluation, and treatment of
chronic kidney disease (CKD). Glomerular filtration rate (GFR) is widely accepted as the best
overall measure of kidney function. For this reason, CKD is defined based on the level of
GFR (Box 1), and clinical recommendations for individuals at increased risk of CKD and for
patients at each stage of CKD include assessment of GFR (Table 1). This article reviews the
physiologic basis of GFR, the methods for measurement of GFR, and new recommendations …