[PDF][PDF] Long-term survival for patients with non–small-cell lung cancer with intratumoral lymphoid structures
MC Dieu-Nosjean, M Antoine, C Danel… - Journal of Clinical …, 2008 - researchgate.net
MC Dieu-Nosjean, M Antoine, C Danel, D Heudes, M Wislez, V Poulot, N Rabbe, L Laurans…
Journal of Clinical Oncology, 2008•researchgate.netPurpose It has been established that the immune system plays an important role in tumor
rejection. There is also compelling evidence that immune responses can develop
independently of secondary lymphoid organs in tertiary lymphoid structures. We studied the
presence and the correlation of tertiary lymphoid structures with clinical outcome in non–
small-cell lung cancer (NSCLC), as the prognostic value of these structures in patients with
cancer had not yet been established.
rejection. There is also compelling evidence that immune responses can develop
independently of secondary lymphoid organs in tertiary lymphoid structures. We studied the
presence and the correlation of tertiary lymphoid structures with clinical outcome in non–
small-cell lung cancer (NSCLC), as the prognostic value of these structures in patients with
cancer had not yet been established.
Purpose
It has been established that the immune system plays an important role in tumor rejection. There is also compelling evidence that immune responses can develop independently of secondary lymphoid organs in tertiary lymphoid structures. We studied the presence and the correlation of tertiary lymphoid structures with clinical outcome in non–small-cell lung cancer (NSCLC), as the prognostic value of these structures in patients with cancer had not yet been established.
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