The endocrinological basis of recurrent miscarriages

N Potdar, JC Konje - Current Opinion in Obstetrics and …, 2005 - journals.lww.com
N Potdar, JC Konje
Current Opinion in Obstetrics and Gynecology, 2005journals.lww.com
Abnormal secretory endometrial changes may adversely affect the early pregnancy
outcome. Other dating techniques using biochemical and molecular markers of endometrial
function may prove useful in predicting outcome. Use of progestogens with or without
estrogens for prevention of recurrent miscarriage needs to be investigated further in larger
randomized controlled trials. The role of endocannabinoids and agents modulating their
receptors are potentially very exciting areas to be explored further.
Summary
Abnormal secretory endometrial changes may adversely affect the early pregnancy outcome. Other dating techniques using biochemical and molecular markers of endometrial function may prove useful in predicting outcome. Use of progestogens with or without estrogens for prevention of recurrent miscarriage needs to be investigated further in larger randomized controlled trials. The role of endocannabinoids and agents modulating their receptors are potentially very exciting areas to be explored further.
Lippincott Williams & Wilkins