Acute liver failure

RQ Gill, RK Sterling - Journal of clinical gastroenterology, 2001 - journals.lww.com
Acute liver failure (ALF) is defined as hepatic encephalopathy complicating acute liver injury.
The most common etiologies are acute viral hepatitis A and B, medication overdose (eg,
acetaminophen), idiosyncratic drug reactions, ingestion of other toxins (eg, amanita
mushroom poisoning), and metabolic disorders (eg, Reye's syndrome). Despite advances in
intensive care management, mortality continues to be high (40–80%) and is partly related to
ALF's complications, such as cerebral edema, sepsis, hypoglycemia, gastrointestinal …