[HTML][HTML] RBCK1, a protein kinase CβI (PKCβI)-interacting protein, regulates PKCβ-dependent function
A Vallentin, D Mochly-Rosen - Journal of biological chemistry, 2007 - ASBMB
RBCK1 (RBCC protein interacting with PKC 1) has originally been identified as a protein
kinase CβI (PKCβI)-binding partner by a two-hybrid screen and as one of the gene
transcripts that increases during adult cardiac hypertrophy. To address whether RBCK1 and
PKCβI functions are interconnected, we used cultured neonatal myocytes where we
previously found that the activity of PKCβI is required for an increase in cell size, also called
hypertrophy. In this study, we showed that acute treatment of cardiac myocytes with …
kinase CβI (PKCβI)-binding partner by a two-hybrid screen and as one of the gene
transcripts that increases during adult cardiac hypertrophy. To address whether RBCK1 and
PKCβI functions are interconnected, we used cultured neonatal myocytes where we
previously found that the activity of PKCβI is required for an increase in cell size, also called
hypertrophy. In this study, we showed that acute treatment of cardiac myocytes with …