The tuberous sclerosis complex
PB Crino, KL Nathanson… - New England Journal of …, 2006 - Mass Medical Soc
PB Crino, KL Nathanson, EP Henske
New England Journal of Medicine, 2006•Mass Medical SocThe tuberous sclerosis complex (TSC), a multisystem, autosomal dominant disorder
affecting children and adults, results from mutations in one of two genes, TSC1 (encoding
hamartin) or TSC2 (encoding tuberin). In this article, the current knowledge of the
pathogenesis of the disease and its management are discussed.
affecting children and adults, results from mutations in one of two genes, TSC1 (encoding
hamartin) or TSC2 (encoding tuberin). In this article, the current knowledge of the
pathogenesis of the disease and its management are discussed.
The tuberous sclerosis complex (TSC), a multisystem, autosomal dominant disorder affecting children and adults, results from mutations in one of two genes, TSC1 (encoding hamartin) or TSC2 (encoding tuberin). In this article, the current knowledge of the pathogenesis of the disease and its management are discussed.
The New England Journal Of Medicine