Patterns of proliferation related to vasculature in human head-and-neck carcinomas before and after transplantation in nude mice
KIEM Wijffels, JHAM Kaanders, HAM Marres… - International Journal of …, 2001 - Elsevier
Purpose: The predictive potential of tumor cell kinetic parameters may be improved when
they are studied in relation to other microenvironmental parameters. The purpose of this
investigation was to quantitatively categorize human tumor samples according to
proliferation patterns. Second, it was examined whether these characteristics are retained
after xenotransplantation. Methods and Materials: Fifty tumor samples from head-and-neck
cancer patients were immunohistochemically stained for Ki-67 and vessels. Also, parts of the …
they are studied in relation to other microenvironmental parameters. The purpose of this
investigation was to quantitatively categorize human tumor samples according to
proliferation patterns. Second, it was examined whether these characteristics are retained
after xenotransplantation. Methods and Materials: Fifty tumor samples from head-and-neck
cancer patients were immunohistochemically stained for Ki-67 and vessels. Also, parts of the …