Hereditary gastrointestinal polyposis syndromes
RC Haggitt, BJ Reid - The American journal of surgical pathology, 1986 - journals.lww.com
Hereditary gastrointestinal polyposis syndromes can be divided into adenomatous and
hamartomatous types. Familial adenomatous polyposis coli (FAPC) is the prototype
adenomatous polyposis syndrome and is defined by the autosomal dominant transmission
of multiple (more than 100) colorectal adenomas. Virtually all affected patients develop
colorectal carcinoma if untreated. Adenomas may develop also in the stomach and small
bowel in FAPC patients, but the incidence of carcinoma in these sites is low. A variety of …
hamartomatous types. Familial adenomatous polyposis coli (FAPC) is the prototype
adenomatous polyposis syndrome and is defined by the autosomal dominant transmission
of multiple (more than 100) colorectal adenomas. Virtually all affected patients develop
colorectal carcinoma if untreated. Adenomas may develop also in the stomach and small
bowel in FAPC patients, but the incidence of carcinoma in these sites is low. A variety of …