Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study
J Douwes, R van Strien, G Doekes, J Smit… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Exposure to microbial agents might inhibit the development of atopy and
asthma. OBJECTIVE: We measured the association between microbial exposure assessed
at 3 months and the development of atopic sensitization and doctor-diagnosed (DD) asthma
and wheeze in the first 4 years in a birth cohort study of children with atopic mothers.
METHODS: Endotoxin, fungal (1→ 3)-β-D-glucans, extracellular polysaccharides from the
genera Penicillium and Aspergillus (EPS-Pen/Asp), and dust on living room floors were …
asthma. OBJECTIVE: We measured the association between microbial exposure assessed
at 3 months and the development of atopic sensitization and doctor-diagnosed (DD) asthma
and wheeze in the first 4 years in a birth cohort study of children with atopic mothers.
METHODS: Endotoxin, fungal (1→ 3)-β-D-glucans, extracellular polysaccharides from the
genera Penicillium and Aspergillus (EPS-Pen/Asp), and dust on living room floors were …