Morphological development of microglia in the postnatal rat brain: a quantitative study

D Orłowski, Z Sołtys, K Janeczko - International journal of developmental …, 2003 - Elsevier
Morphological transformation of lectin-positive microglia/macrophages in the developing rat
cerebral hemisphere was analysed using quantitative methods. During the first postnatal
month, the cells showed increases in their size and fractal dimension accompanied by a
simultaneous decrease in their solidity. Regional variations in dynamics of the process
indicated the existence of spatio-temporal developmental gradients within the cerebral
hemisphere wall which might correspond with regional patterns of neuronal differentiation …