[HTML][HTML] The emergence of Lyme disease
AC Steere, J Coburn, L Glickstein - The Journal of clinical …, 2004 - Am Soc Clin Investig
AC Steere, J Coburn, L Glickstein
The Journal of clinical investigation, 2004•Am Soc Clin InvestigSince its identification nearly 30 years ago, Lyme disease has continued to spread, and
there have been increasing numbers of cases in the northeastern and north central US. The
Lyme disease agent, Borrelia burgdorferi, causes infection by migration through tissues,
adhesion to host cells, and evasion of immune clearance. Both innate and adaptive immune
responses, especially macrophage-and antibody-mediated killing, are required for optimal
control of the infection and spirochetal eradication. Ecological conditions favorable to the …
there have been increasing numbers of cases in the northeastern and north central US. The
Lyme disease agent, Borrelia burgdorferi, causes infection by migration through tissues,
adhesion to host cells, and evasion of immune clearance. Both innate and adaptive immune
responses, especially macrophage-and antibody-mediated killing, are required for optimal
control of the infection and spirochetal eradication. Ecological conditions favorable to the …
Since its identification nearly 30 years ago, Lyme disease has continued to spread, and there have been increasing numbers of cases in the northeastern and north central US. The Lyme disease agent, Borrelia burgdorferi, causes infection by migration through tissues, adhesion to host cells, and evasion of immune clearance. Both innate and adaptive immune responses, especially macrophage- and antibody-mediated killing, are required for optimal control of the infection and spirochetal eradication. Ecological conditions favorable to the disease, and the challenge of prevention, predict that Lyme disease will be a continuing public health concern.
The Journal of Clinical Investigation