[HTML][HTML] Argonautes and company: sailing against the wind
SN Bhattacharyya, W Filipowicz - Cell, 2007 - cell.com
SN Bhattacharyya, W Filipowicz
Cell, 2007•cell.comThe 3′-untranslated region (UTR) of mRNA is crucial for posttranscriptional regulation. In
this issue, Vasudevan and Steitz (2007) report a new function for AGO2 and FXR1—two
proteins that have been linked to the regulation of microRNAs and translation repression.
AGO2 and FXR1 bind to the AU-rich element in the 3′-UTR of TNFα mRNA, unexpectedly
activating its translation in a cell growth-dependent manner.
this issue, Vasudevan and Steitz (2007) report a new function for AGO2 and FXR1—two
proteins that have been linked to the regulation of microRNAs and translation repression.
AGO2 and FXR1 bind to the AU-rich element in the 3′-UTR of TNFα mRNA, unexpectedly
activating its translation in a cell growth-dependent manner.
The 3′-untranslated region (UTR) of mRNA is crucial for posttranscriptional regulation. In this issue, Vasudevan and Steitz (2007) report a new function for AGO2 and FXR1—two proteins that have been linked to the regulation of microRNAs and translation repression. AGO2 and FXR1 bind to the AU-rich element in the 3′-UTR of TNFα mRNA, unexpectedly activating its translation in a cell growth-dependent manner.
cell.com