Demyelination is a pathological hallmark of multiple sclerosis (MS), a chronic autoimmune
disorder of the central nervous system (CNS) that affects mainly young people in western
countries. Recent studies have shown that remyelination can be accomplished by supplying
demyelinated regions with myelinogenic cells or neural stem cells via transplantation. The
remyelinating effect of these cells may be via one or more mechanisms, including: 1) as an
immunomodulator by producing soluble factors; 2) direct cell replacement by differentiating …