The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS
JS Henkel, DR Beers, L Siklós, SH Appel - Molecular and Cellular …, 2006 - Elsevier
We recently demonstrated increased dendritic cells (potent antigen-presenting cells) and
MCP-1 (monocyte, T-cell, and dendritic cell attracting chemokine) levels in ALS spinal cord
tissue. Additionally, we presented data suggesting that dendritic cells might be contributing
to the pathogenesis. To determine whether MCP-1 and dendritic cells are present in the
mSOD1 mouse and how early in the disease process they are involved, we examined
mSOD1 and control spinal cord tissue at different ages using real-time RT-PCR and …
MCP-1 (monocyte, T-cell, and dendritic cell attracting chemokine) levels in ALS spinal cord
tissue. Additionally, we presented data suggesting that dendritic cells might be contributing
to the pathogenesis. To determine whether MCP-1 and dendritic cells are present in the
mSOD1 mouse and how early in the disease process they are involved, we examined
mSOD1 and control spinal cord tissue at different ages using real-time RT-PCR and …