Origin and fate of pendrin-positive intercalated cells in developing mouse kidney

HK Song, WY Kim, HW Lee, EY Park… - Journal of the …, 2007 - journals.lww.com
Pendrin is an apical anion exchanger found in type B and nonA-nonB intercalated cells that
is involved in bicarbonate secretion. The purpose of this study was to establish the origin
and fate of pendrin-positive intercalated cells in the mouse kidney. Using
immunohistochemistry, we found that pendrin-positive cells first appeared in the connecting
tubule at embryonic day 14 (E14) and subsequently in the medullary collecting duct at E18.
Most of the pendrin-positive cells in the connecting tubule were nonA–nonB intercalated …