Pilot study of interferon gamma for chronic hepatitis C

A Soza, T Heller, M Ghany, G Lutchman, TJ Liang… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Currently, there are no effective therapies available for patients with
chronic hepatitis C who have failed to respond to optimal interferon alfa-based regimens.
The aims of this pilot study were to assess the antiviral activity and safety of interferon
gamma in chronic hepatitis C. METHODS: Patients with chronic hepatitis C, genotype 1, who
had not responded to or who had relapsed after therapy with interferon alfa and ribavirin
were enrolled in a trial of interferon gamma 1b given in doses of 100, 200 or 400μg …