Differential MAP kinases activation during semaphorin3A-induced repulsion or apoptosis of neural progenitor cells
D Bagnard, N Sainturet, D Meyronet, M Perraut… - Molecular and Cellular …, 2004 - Elsevier
Semaphorins are multifunctional factors implicated in various developmental processes.
Little is known about the intracellular pathways ensuring appropriate signal transduction that
encode the diverse functions observed. In this study, we investigated whether mitogen-
activated protein kinases (MAPK), which are key elements of signal transduction in
eukaryotic cells, were activated during semaphorin 3A (Sema3A)-induced repulsion or
apoptosis of neural progenitor cells. We found that selective recruitment of the ERK1/2 …
Little is known about the intracellular pathways ensuring appropriate signal transduction that
encode the diverse functions observed. In this study, we investigated whether mitogen-
activated protein kinases (MAPK), which are key elements of signal transduction in
eukaryotic cells, were activated during semaphorin 3A (Sema3A)-induced repulsion or
apoptosis of neural progenitor cells. We found that selective recruitment of the ERK1/2 …