Causes and timing of death in patients with ARDS
RD Stapleton, BM Wang, LD Hudson, GD Rubenfeld… - Chest, 2005 - Elsevier
Background Since the early 1980s, case fatality of patients with ARDS has decreased, and
explanations are unclear Design and methods Using identical definitions of ARDS and
organ failure, we analyzed consecutive cohorts of patients meeting syndrome criteria at our
institution in 1982 (n= 46), 1990 (n= 112), 1994 (n= 99), and 1998 (n= 205) to determine
causes and timing of death Results Overall case fatality has decreased from 68% in 1981–
1982 to a low of 29% in 1996, plateauing since the mid-1990s (p= 0.001 for trend). Sepsis …
explanations are unclear Design and methods Using identical definitions of ARDS and
organ failure, we analyzed consecutive cohorts of patients meeting syndrome criteria at our
institution in 1982 (n= 46), 1990 (n= 112), 1994 (n= 99), and 1998 (n= 205) to determine
causes and timing of death Results Overall case fatality has decreased from 68% in 1981–
1982 to a low of 29% in 1996, plateauing since the mid-1990s (p= 0.001 for trend). Sepsis …