[HTML][HTML] A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans
KA Leˆ, D Faeh, R Stettler, M Ith, R Kreis… - The American journal of …, 2006 - Elsevier
Background: High fructose consumption is suspected to be causally linked to the epidemics
of obesity and metabolic disorders. In rodents, fructose leads to insulin resistance and
ectopic lipid deposition. In humans, the effects of fructose on insulin sensitivity remain
debated, whereas its effect on ectopic lipids has never been investigated. Objective: We
assessed the effect of moderate fructose supplementation on insulin sensitivity (IS) and
ectopic lipids in healthy male volunteers (n= 7). Design: IS, intrahepatocellular lipids (IHCL) …
of obesity and metabolic disorders. In rodents, fructose leads to insulin resistance and
ectopic lipid deposition. In humans, the effects of fructose on insulin sensitivity remain
debated, whereas its effect on ectopic lipids has never been investigated. Objective: We
assessed the effect of moderate fructose supplementation on insulin sensitivity (IS) and
ectopic lipids in healthy male volunteers (n= 7). Design: IS, intrahepatocellular lipids (IHCL) …