IgG antibodies against microorganisms and atopic disease in Danish adults: the Copenhagen Allergy Study

A Linneberg, C Østergaard, M Tvede… - Journal of Allergy and …, 2003 - Elsevier
Background: Seropositivity to food-borne and orofecal microorganisms (hepatitis A virus,
Helicobacter pylori, and Toxoplasma gondii), which are considered to be markers of poor
hygiene, has been reported to be associated with a lower prevalence of atopy. In contrast,
colonization of the gut with Clostridium difficile, a potential intestinal bacterial pathogen, in
early childhood may be associated with a higher prevalence of atopy. Objective: The
objective of this study was to investigate the association between atopy and exposure to 2 …