Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin …
A Di Sabatino, L Rovedatti, MM Rosado, R Carsetti… - Human pathology, 2009 - Elsevier
Mucosal addressin cell adhesion molecule 1, expressed on gut endothelial cells, in
conjunction with integrin α4β7, expressed on lymphocytes, is critical in lymphocyte homing
to the gut. The mucosal addressin cell adhesion molecule 1/integrin α4β7 pathway is
involved in the pathogenesis of chronic intestinal inflammation by recruiting lymphocytes
into inflamed gut. We explored the duodenal expression of mucosal addressin cell adhesion
molecule 1 and the peripheral T-cell expression of integrin α4β7 in patients with celiac …
conjunction with integrin α4β7, expressed on lymphocytes, is critical in lymphocyte homing
to the gut. The mucosal addressin cell adhesion molecule 1/integrin α4β7 pathway is
involved in the pathogenesis of chronic intestinal inflammation by recruiting lymphocytes
into inflamed gut. We explored the duodenal expression of mucosal addressin cell adhesion
molecule 1 and the peripheral T-cell expression of integrin α4β7 in patients with celiac …