Induction of the intercellular adhesion molecule (ICAM-1) on squamous cell carcinoma by interferon gamma
RL Scher, WM Koch… - Archives of Otolaryngology …, 1993 - jamanetwork.com
• Objective.—To determine if the cell surface antigen, the intercellular adhesion molecule 1
(ICAM-1), is expressed on head and neck (H&N) squamous cell carcinoma (SCC) cell lines,
and if treatment with interferon gamma (IFN-γ) enhances the expression of the antigen.
Intercellular adhesion molecule 1 mediates effector cell adhesion, activation, and function in
inflammatory and immunologic reactions, and it may be important in the generation of
antitumor immune surveillance and cytotoxicity against H&N SCC. Materials.—Four human …
(ICAM-1), is expressed on head and neck (H&N) squamous cell carcinoma (SCC) cell lines,
and if treatment with interferon gamma (IFN-γ) enhances the expression of the antigen.
Intercellular adhesion molecule 1 mediates effector cell adhesion, activation, and function in
inflammatory and immunologic reactions, and it may be important in the generation of
antitumor immune surveillance and cytotoxicity against H&N SCC. Materials.—Four human …