[HTML][HTML] Structure of the Rad50· Mre11 DNA repair complex fromSaccharomyces cerevisiae by electron microscopy
DE Anderson, KM Trujillo, P Sung… - Journal of Biological …, 2001 - ASBMB
The RAD50 gene of Saccharomyces cerevisiae is one of several genes required for
recombinational repair of double-strand DNA breaks during vegetative growth and for
initiation of meiotic recombination. Rad50 forms a complex with two other proteins, Mre11
and Xrs2, and this complex is involved in double-strand break formation and processing.
Rad50 has limited sequence homology to the structural maintenance of chromosomes
(SMC) family of proteins and shares the same domain structure as SMCs: N-and C-terminal …
recombinational repair of double-strand DNA breaks during vegetative growth and for
initiation of meiotic recombination. Rad50 forms a complex with two other proteins, Mre11
and Xrs2, and this complex is involved in double-strand break formation and processing.
Rad50 has limited sequence homology to the structural maintenance of chromosomes
(SMC) family of proteins and shares the same domain structure as SMCs: N-and C-terminal …