[HTML][HTML] A blocking antibody to the hyaluronan receptor for endocytosis (HARE) inhibits hyaluronan clearance by perfused liver
Hyaluronan (HA) and chondroitin sulfate clearance from lymph and blood is mediated by the
hyaluronan receptor for endocytosis (HARE). The purification and molecular cloning (Zhou,
B., Weigel, JA, Saxena, A., and Weigel, PH (2002) Mol. Biol. Cell 13, 2853–2868) of this cell
surface receptor were finally achieved after we developed monoclonal antibodies (mAbs)
against HARE. There are actually two independent isoreceptors for HA, which in rat are
designated the 175-kDa HARE and 300-kDa HARE. Only one mAb (number 174) effectively …
hyaluronan receptor for endocytosis (HARE). The purification and molecular cloning (Zhou,
B., Weigel, JA, Saxena, A., and Weigel, PH (2002) Mol. Biol. Cell 13, 2853–2868) of this cell
surface receptor were finally achieved after we developed monoclonal antibodies (mAbs)
against HARE. There are actually two independent isoreceptors for HA, which in rat are
designated the 175-kDa HARE and 300-kDa HARE. Only one mAb (number 174) effectively …