Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response
DA Shoskes, Q Albakri, K Thomas, D Cook - The Journal of urology, 2002 - Elsevier
PURPOSE: The chronic pelvic pain syndrome is a common disorder of unknown etiology.
Elevated cytokines in prostate fluid and semen are frequent findings. We studied genetic
polymorphisms that can alter cytokine gene expression in men with the chronic pelvic pain
syndrome. MATERIALS AND METHODS: Genomic DNA was extracted from blood from 36
men with the chronic pelvic pain syndrome. Reversed sequence specific oligonucleotide
probing was used to genotype the polymorphisms for cytokine promoter sites, namely tumor …
Elevated cytokines in prostate fluid and semen are frequent findings. We studied genetic
polymorphisms that can alter cytokine gene expression in men with the chronic pelvic pain
syndrome. MATERIALS AND METHODS: Genomic DNA was extracted from blood from 36
men with the chronic pelvic pain syndrome. Reversed sequence specific oligonucleotide
probing was used to genotype the polymorphisms for cytokine promoter sites, namely tumor …