Prostatein or steroid binding protein (PSBP) induces experimental autoimmune prostatitis (EAP) in NOD mice

V Rivero, C Carnaud, CM Riera - Clinical immunology, 2002 - Elsevier
In a previous study, we showed that nonobese diabetic (NOD) mice, a strain that present an
inherited predisposition to develop both spontaneous and induced autoimmune lesions, are
susceptible to the induction of experimental autoimmune prostatitis (EAP), developing a
severe inflammatory reaction in the prostate, accompanied by humoral and T-cell-mediated
responses. In this study we asked whether the protein steroid binding protein (PSBP) or
prostatein (a major autoantigen in the rat model of EAP) is a potential autoantigen in the …