Characteristics of autoimmune thyroid disease occurring as a late complication of immune reconstitution in patients with advanced human immunodeficiency virus …

F Chen, SL Day, RA Metcalfe, G Sethi, MS Kapembwa… - Medicine, 2005 - journals.lww.com
Experimental evidence from animal models has provided a framework for our current
understanding of autoimmune disease pathogenesis and supports the importance of genetic
predisposition, molecular mimicry, and immune dysregulation. However, only recently has
evidence emerged to support the role of immune dysregulation in human organ-specific
autoimmune disease. In the current study of the" late" manifestation of autoimmune thyroid
disease (AITD) in a cohort of human immunodeficiency virus (HIV)-positive patients …