Identification of a nuclear protein matrix

R Berezney, DS Coffey - Biochemical and biophysical research …, 1974 - Elsevier
R Berezney, DS Coffey
Biochemical and biophysical research communications, 1974Elsevier
The structural framework of the rat liver nucleus has been identified and consists of a
nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5%
phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide
fractions in the molecular weight range of 60–70,000 daltons.
Abstract
The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60–70,000 daltons.
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