[HTML][HTML] A distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis

F Le Naour, F Brichory, DE Misek, C Brechot… - Molecular & Cellular …, 2002 - ASBMB
Chronic infections with hepatitis B (HBV) and hepatitis C (HCV) viruses are major risk factors
for hepatocellular carcinoma (HCC). We have utilized a proteomic approach to determine
whether a distinct repertoire of autoantibodies can be identified in HCC. Sera from 37
patients with HCC and 31 subjects chronically infected with HBV or HCV without HCC were
investigated. Sera from 116 patients with other cancers, three patients with systemic lupus
erythematosus, and 24 healthy subjects were utilized as controls. We report the identification …