Interleukin–6, Hepatocyte Growth Factor, and Their Receptors in Biliary Epithelial Cells During A Type I Ductular Reaction in Mice: Interactions Between the Periductal …
Z Liu, T Sakamoto, T Ezure, S Yokomuro, N Murase… - Hepatology, 1998 - journals.lww.com
Abstract The interleukin–6 (IL–6)/gp–80 and hepatocyte growth factor (HGF)/met
ligand/receptor systems have been shown to stimulate biliary epithelial cell (BEC) DNA
synthesis in vitro. The mRNA and protein production of these two in vitro mitogens were
mapped in vivo during the first week after bile duct ligation (BDL) when peak BEC DNA
synthesis is seen. Changes around the biliary tree were compared with those seen in the
peripheral liver using a combination of Northern blotting and a unique biliary tree isolation …
ligand/receptor systems have been shown to stimulate biliary epithelial cell (BEC) DNA
synthesis in vitro. The mRNA and protein production of these two in vitro mitogens were
mapped in vivo during the first week after bile duct ligation (BDL) when peak BEC DNA
synthesis is seen. Changes around the biliary tree were compared with those seen in the
peripheral liver using a combination of Northern blotting and a unique biliary tree isolation …