Hepatocellular carcinoma (HCC) is one of the most common malignant tumours worldwide.
The major aetiologies and risk factors for the development of HCC are well defined and
some of the multiple steps involved in hepatocarcinogenesis have been elucidated in recent
years. However, no clear picture of how and in what sequence these factors interact at the
molecular level has emerged yet. Malignant transformation of hepatocytes may occur as a
consequence of various aetiologies, such as chronic viral hepatitis, alcohol, and metabolic …