Human and mouse disorders of pigmentation
RA Spritz, PW Chiang, N Oiso, A Alkhateeb - Current opinion in genetics & …, 2003 - Elsevier
RA Spritz, PW Chiang, N Oiso, A Alkhateeb
Current opinion in genetics & development, 2003•ElsevierDisorders of pigmentation were among the first genetic diseases ever recognized because
of their visually striking clinical phenotypes, resulting from defects of pigmentary
melanocytes. Recent years have seen remarkable progress in understanding these
diseases, largely as a result of the systematic parallel study of human patients and inbred
mice with similar phenotypes. Our understanding of disorders of pigmentation indicates that
these diseases may be most usefully considered as abnormalities of melanocyte …
of their visually striking clinical phenotypes, resulting from defects of pigmentary
melanocytes. Recent years have seen remarkable progress in understanding these
diseases, largely as a result of the systematic parallel study of human patients and inbred
mice with similar phenotypes. Our understanding of disorders of pigmentation indicates that
these diseases may be most usefully considered as abnormalities of melanocyte …
Disorders of pigmentation were among the first genetic diseases ever recognized because of their visually striking clinical phenotypes, resulting from defects of pigmentary melanocytes. Recent years have seen remarkable progress in understanding these diseases, largely as a result of the systematic parallel study of human patients and inbred mice with similar phenotypes. Our understanding of disorders of pigmentation indicates that these diseases may be most usefully considered as abnormalities of melanocyte development, function, or survival.
Elsevier